The Functional Significance of a Novel Conceptualization of Intrusion Symptoms of PTSD

Introduction Intrusion symptoms are a core defining feature of posttraumatic stress disorder (PTSD). It was recently proposed that intrusions may be comprised two distinct underlying processes: internally-cued (e.g., memories), and externally-cued reactions to one’s environment). Preliminary empirical evidence demonstrated superior fit an 8-factor model PTSD, separating intrusion into in symptom cluster over other factor models PTSD. However, whether these clusters related differently with functional outcomes not investigated previously. Objectives This is the first study examine correlates PTSD assess clinical scientific relevance. Methods Participants included 7460 veterans discharged from 40 VA residential treatment programs (RRTPs) across United States fiscal years 2018 through 2020. Demographic data collected using self-report form during admission process. Symptoms anxiety, depression, emotional physical functioning were assessed Checklist for DSM-5, Patient Health Questionnaire-9, Generalized Anxiety Disorder Questionnaire-7, corresponding subscales Short Form 12-item Survey, respectively. Latent network modeling used test Structural equation modelling investigate associations between factors outcomes. All adjusted demographic characteristics, standardized. Results The model, separate factors, showed good (CFI 0.965, RMSEA 0.045, χ 2 2453.022, P <.001). Internally-cued negatively associated positively functioning. No relationship depression or anxiety found. In contrast, but depression. Conclusions provides initial support utility distinguishing internally- Consequently, researchers focusing on biological underpinnings imaging genetic studies) should account differences origin cue triggering intrusions. Our findings potential relevance as they might help patients adapt their coping strategies depending originate internally thoughts) externally loud noises). Disclosure Interest None Declared